7-epi-Cephalomannine

• 产品号: C258515
• CAS号: 150547-36-7
• 分子式: C45H53NO14
• 分子量: 831.90062

产品别名

• 标题: 7-epi-Cephalomannine
• IUPAC标准名: (1S,2S,3R,4S,7R,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-[(2E)-2-methylbut-2-enamido]-3-phenylpropanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC传统名: (1S,2S,3R,4S,7R,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-[(2E)-2-methylbut-2-enamido]-3-phenylpropanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• 别名: (αR,βS)-α-Hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]benzenepropanoic Acid (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester

产品登记号

• CAS号: 150547-36-7

产品详细信息

详细说明 (English)

The C-7 epimer of the taxane Cephalomannine (C258500) isolated from Taxus x media cv. 'Hicksii' needles.

参考文献

• Stenken, J., et al.: J. Pharm. Sci., 86, 958 (1997)
• Kobayashi, J., et al.: Bioorg. Med. Chem. Lett., 8, 1555 (1997)
• Andreu, J., et al.: Biochemistry, 40, 11975 (1997)
• Markman, M., et al.: J. Clin. Oncol., 24, 988 (1997)