CDDO Imidazolide

• 产品号: C228090
• CAS号: 443104-02-7
• 分子式: C34H43N3O3
• 分子量: 541.72352
• 保 存: Amber Vial, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: CDDO Imidazolide
• IUPAC标准名: (4aR,6aS,6bR,8aS,12aS,12bR,14bS)-8a-(1H-imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-2-carbonitrile
• IUPAC传统名: (4aR,6aS,6bR,8aS,12aS,12bR,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,7,8,9,10,12,12a,12b-decahydropicene-2-carbonitrile
• 别名: CDDO-Im; 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid imidazolide; RTA 403; TP 235

产品登记号

• CAS号: 443104-02-7

产品性质

• 外观: Pale Yellow Solid
• 熔点: 180-192°C (dec.)
• 溶解度: Chloroform
• 保存条件: Amber Vial, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

CDDO Imidozolide (CDDO-Im) is a synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Studies show that CDDO-Im is highly active in suppressing cellular prolif

参考文献

• Hughes, D.T. et al.: Cancer Invest., 26, 118 (2008)
• Place, A.E. et al.: Clin. Cancer Res., 9, 2798 (2008)
• Samudio, I. et al.: J. Biol. Chem., 280, 36273 (2008)