Carbovir Triphosphate Triethylamine Salt

• 产品号: C177755
• 分子式: C17H31N6O11P3
• 分子量: 588.382923

产品别名

• 标题: Carbovir Triphosphate Triethylamine Salt
• IUPAC标准名: ({[({[(1S,4R)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)cyclopent-2-en-1-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid; triethylamine
• IUPAC传统名: ({[(1S,4R)-4-(2-amino-6-oxo-3H-purin-9-yl)cyclopent-2-en-1-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid; triethylamine
• 别名: cis-(±)-P-[[4-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-2-cyclopenten-1-yl]methyl] Ester Triphosphoric Acid Triethylamine Salt; (±)-Carbovir Triphosphate Triethylamine Salt; rel-P-[[(1R,4S)-4-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-2-cyclopenten-1-yl]methyl] Ester Triphosphoric Acid Triethylamine Salt

产品详细信息

详细说明 (English)

An active metabolite of Abacavir (A104990) used to study the molecular mechanism of inhibition and drug resistance for HIV-1 reverse transcriptase.

参考文献

• Ray, A.S. et al.: Biochem., 41, 5150 (2002)
• Goicochea, M. et al.: J. Clin. Pharmacol., 50, 968 (2002)
• Hawkins, T. et al.: JAIDS, J. Acq. Imm. Defic. Synd., 39, 406 (2002)