Canagliflozin

• 产品号: C175190
• CAS号: 842133-18-0
• 分子式: C24H25FO5S
• 分子量: 444.5157032

产品别名

• 标题: Canagliflozin
• IUPAC标准名: (2S,4R,5S)-2-(3-{[5-(4-fluorophenyl)thiophen-2-yl]methyl}-4-methylphenyl)-6-(hydroxymethyl)oxane-3,4,5-triol
• IUPAC传统名: (2S,4R,5S)-2-(3-{[5-(4-fluorophenyl)thiophen-2-yl]methyl}-4-methylphenyl)-6-(hydroxymethyl)oxane-3,4,5-triol
• 别名: (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol

产品登记号

• CAS号: 842133-18-0

产品详细信息

详细说明 (English)

Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the trea

参考文献

• Chao, E. et al.: Drug Fut., 36, 351 (2011)
• Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011)
• Kipnes, M.S.: Clin. Invest., 1, 145 (2011)