2'-O-(tert-Butyldimethylsilyl)-6α-hydroxy 7-epi-Paclitaxel

• 产品号: B691290
• CAS号: 165065-08-7
• 分子式: C53H65NO15Si
• 分子量: 984.1664

产品别名

• 标题: 2'-O-(tert-Butyldimethylsilyl)-6α-hydroxy 7-epi-Paclitaxel
• IUPAC标准名: (1S,2S,4S,7R,8S,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-2-[(tert-butyldimethylsilyl)oxy]-3-phenyl-3-(phenylformamido)propanoyl]oxy}-1,8,9-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC传统名: (1S,2S,4S,7R,8S,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-2-[(tert-butyldimethylsilyl)oxy]-3-phenyl-3-(phenylformamido)propanoyl]oxy}-1,8,9-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate

产品登记号

• CAS号: 165065-08-7

产品性质

• 外观: White Solid
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate
• 溶解度: Methanol

产品详细信息

详细说明 (English)

6α-Hydroxypaclitaxel derivative.

参考文献

• Monsarrat, B., et al.: Drug Metab. Dispos., 18, 895 (1990)
• Walle, T., et al.: Biochem. Pharm., 46, 1661 (1990)
• Harris, J., et al.: J. Med. Chem., 37, 706 (1990)