Brivanib Alaninate

• 产品号: B677640
• CAS号: 649735-63-7
• 分子式: C19H19FN4O3
• 分子量: 370.3775632

产品别名

• 标题: Brivanib Alaninate
• IUPAC标准名: (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol
• IUPAC传统名: (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol
• 别名: BMS 582664; L-Alanine (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethyl Ester

产品登记号

• CAS号: 649735-63-7

产品详细信息

详细说明 (English)

A novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinase inhibitor. Antitumor agent.

参考文献

• Ellis, L., et al.: Eur. J. Cancer, 32A, 2451 (1996)
• Klagsbrun, M., et al.: Chem. Biol., 6, R217 (1996)
• Auguste, P., et al.: Cancer Res., 61, 1717 (1996)
• Bhide, R., et al.: J. Med. Chem., 49, 2143 (1996)