Bodipy Cyclopamine-d10

• 产品号: B674802
• 分子式: C49H70BF2N5O4
• 分子量: 841.9190064

产品别名

• 标题: Bodipy Cyclopamine-d10
• IUPAC标准名: 4-(2-{[5-({2-[(3S,7'aR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3'H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-4'-yl]ethyl}carbamoyl)(^2H₁₀)pentyl]carbamoyl}ethyl)-2,2-difluoro-10,12-dimethyl-1λ^5,3-diaza-2-boratricyclo[7.3.0.0^3,^7]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide
• IUPAC传统名: 4-(2-{[5-({2-[(3S,7'aR)-3-hydroxy-3',6',10,11b-tetramethyl-2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a-hexadecahydro-1H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-4'-yl]ethyl}carbamoyl)(^2H₁₀)pentyl]carbamoyl}ethyl)-2,2-difluoro-10,12-dimethyl-1λ^5,3-diaza-2-boratricyclo[7.3.0.0^3,^7]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide

产品详细信息

详细说明 (English)

A labelled fluorescent Cyclopamine derivative that retains potency in Shh signaling inhibition (IC50=150nM).

参考文献

• Chen, K.J., et al.: Genes Develop., 16, 2743 (2002)