BLI 489 Hydrate

• 产品号: B595825
• CAS号: 623564-40-9
• 分子式: C13H10N3NaO4S
• 分子量: 327.29097
• 保 存: Refrigerator

产品别名

• 标题: BLI 489 Hydrate
• IUPAC标准名: sodium (5R)-6-{5H,6H,8H-imidazo[2,1-c][1,4]oxazin-3-ylmethylidene}-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
• IUPAC传统名: sodium (5R)-6-{5H,6H,8H-imidazo[2,1-c][1,4]oxazin-3-ylmethylidene}-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
• 别名: (5R,6Z)-6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt Hydrate

产品登记号

• CAS号: 623564-40-9

产品性质

• 外观: Yellow Solid
• 熔点: >200°C (dec.)
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

BLI-489 is a penem β-lactamase inhibitor, which has shown activity against class A, C, and D β-lactamases. BLI-489 is being tested in combination therapy for drug-resistant bacteria.

参考文献

• Maiti, S., et al.: Curr. Med. Chem., 5, 441 (1998)
• Barnaud, G., et al.: Antimicrob. Agents Chemother., 48, 1040 (1998)
• Szabo, D., et al.: J. Clin. Microbiol., 43, 5058 (1998)