3'-p-O-Benzyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl} Paclitaxel

• 产品号: B288695
• 分子式: C57H58Cl3NO17
• 分子量: 1135.42592
• 保 存: -20°C Freezer

产品别名

• 标题: 3'-p-O-Benzyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl} Paclitaxel
• IUPAC标准名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-[4-(benzyloxy)phenyl]-2-hydroxy-3-(phenylformamido)propanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC传统名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-[4-(benzyloxy)phenyl]-2-hydroxy-3-(phenylformamido)propanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate

产品性质

• 外观: White Solid
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Protected 3’-p-Hydroxy Paclitaxel (H948895), a metabolite of Paclitaxel.

参考文献

• Xiao, X.-Y., et al.: J. Org. Chem., 62, 6029 (1997)
• Sonnichsen, D., et al.: J. Pharmacol. Exp. Ther., 275, 566 (1997)
• Walle, T., et al.: Drug Metab. Dispos., 23, 506 (1997)
• Torres, K., et al.: Cancer Res., 58, 3620 (1997)
• Svojanovsky, S., et al.: J.