[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl[(4-nitro-phenyl)sulfonyl)]amino]propyl]-carbamic Acid tert-Butyl Ester

• 产品号: B279070
• CAS号: 191226-98-9
• 分子式: C25H35N3O7S
• 分子量: 521.6263
• 保 存: Refrigerator

产品别名

• 标题: [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl[(4-nitro-phenyl)sulfonyl)]amino]propyl]-carbamic Acid tert-Butyl Ester
• IUPAC标准名: tert-butyl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-nitrobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate
• IUPAC传统名: tert-butyl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-nitrobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate
• 别名: N-[(1S,2R)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]-carbamic Acid 1,1-Dimethylethyl Ester

产品登记号

• CAS号: 191226-98-9

产品性质

• 外观: White Solid
• 溶解度: Acetone
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor.

参考文献

• Dorsey, B., et al.: J. Med. Chem., 37, 3443 (1994)
• Gong, Y., et al.: Antimicrob. Agents Chemother., 44, 2319 (1994)
• Maeda, K., et al.: J. Biol. Chem., 276, 35194 (1994)