Belotecan-d7 Hydrochloride

• 产品号: B131302
• 分子式: C25H28ClN3O4
• 分子量: 469.96052

产品别名

• 标题: Belotecan-d7 Hydrochloride
• IUPAC标准名: (19S)-19-ethyl-19-hydroxy-10-(2-{[(^2H₇)propan-2-yl]amino}ethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione hydrochloride
• IUPAC传统名: (19S)-19-ethyl-19-hydroxy-10-{2-[(^2H₇)propan-2-ylamino]ethyl}-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione hydrochloride
• 别名: CKD 602-d7; (4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl-d7)amino]ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Hydrochloride

产品详细信息

详细说明 (English)

Labelled Belotecan (B131300). A novel camptothecin-derivative anti-tumor agent. CKD-602-related toxicities induced by IV infusion administration have not yet been evaluated, although the drug is more widely used in clinical settings.

参考文献

• Hertzberg, R., et al.: J. Med. Chem., 32, 715 (1989)
• Hashimoto, H., et al.: Clin. Cancer Res., 1, 369 (1989)
• Dahut, W., et al.: J. Clin. Oncol., 14, 1236 (1989)