Balanol

• 产品号: B115500
• CAS号: 63590-19-2
• 分子式: C28H26N2O10
• 分子量: 550.51344

产品别名

• 标题: Balanol
• IUPAC标准名: 2-[2,6-dihydroxy-4-({[(3R,4R)-3-(4-hydroxybenzamido)azepan-4-yl]oxy}carbonyl)benzoyl]-3-hydroxybenzoic acid
• IUPAC传统名: 2-[2,6-dihydroxy-4-({[(3R,4R)-3-(4-hydroxybenzamido)azepan-4-yl]oxy}carbonyl)benzoyl]-3-hydroxybenzoic acid
• 别名: Ophiocordin; 4-(2-Carboxy-6-hydroxybenzoyl)-3,5-dihydroxybenzoic Acid (3R,4R)-Hexahydro-3-[(4-hydroxybenzoyl)amino]-1H-azepin-4-yl Ester; Azepinostatin; (3R-trans)-Balanol; (-)-Balanol

产品登记号

• CAS号: 63590-19-2

产品详细信息

详细说明 (English)

Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA), important targets in oncology.

参考文献

• Crane, H., et al.: Bioorg. Med. Chem. Lett., 5, 2133 (1995)
• Lai, Y., et al.: J. Med. Chem., 40, 226 (1995)
• Narayana, N., et al.: Biochemistry, 38, 2367 (1995)