Bacitracin F (>80%)

• 产品号: B106530
• CAS号: 22601-63-4
• 分子式: C66H98N16O17S
• 分子量: 1419.64632

产品别名

• 标题: Bacitracin F (>80%)
• IUPAC标准名: (4R)-4-{[(1S)-1-{[(3S,6R,9S,12R,15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-15-(butan-2-yl)-3-(carbamoylmethyl)-6-(carboxymethyl)-9-(1H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}-4-[(2S)-4-methyl-2-{[2-(2-methylbutanoyl)-1,3-thiazol-5-yl]formamido}pentanamido]butanoic acid
• IUPAC传统名: (4R)-4-{[(1S)-1-{[(3S,6R,9S,12R,15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-3-(carbamoylmethyl)-6-(carboxymethyl)-9-(1H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-15-(sec-butyl)-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}-4-[(2S)-4-methyl-2-{[2-(2-methylbutanoyl)-1,3-thiazol-5-yl]formamido}pentanamido]butanoic acid
• 别名: N-[[2-[(2S)-2-Methyl-1-oxobutyl]-4-thiazolyl]carbonyl]-L-leucyl-D-α-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-isoleucyl-D-phenylalanyl-L-histidyl-D-α-aspartyl-L-asparagine (10→4)-Lactam

产品登记号

• CAS号: 22601-63-4

产品详细信息

详细说明 (English)

Bacitracin F is a major Bacitracin (B106500) analog, a peptide antibiotic used as an inhibitor of protein disulfide isomerase (PDI).

参考文献

• Freedman, R., et al.: Cell, 57, 1069 (1989)
• Noiva, R., et al.: J. Biol. Chem., 267, 3553 (1989)
• Ikai, Y., et al.: J. Antibiot., 48, 233 (1989)
• Lovat, P., et al.: Cancer Res., 68, 5363 (1989)
• Byrne, L., et al.: Biochem. J., 423, 209 (1989)