Atorvastatin Calcium Salt

• 产品号: A791750
• CAS号: 134523-03-8
• 分子式: C66H68CaF2N4O10
• 分子量: 1155.3417264
• 保 存: -20°C Freezer

产品别名

• 标题: Atorvastatin Calcium Salt
• IUPAC标准名: calcium bis((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate)
• IUPAC传统名: calcium bis(atorvastatin(1-))
• 别名: Lipitor; CI 981; Tahor; Sortis; (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; Atorvastatin Hemicalcium; YM 548

产品登记号

• CAS号: 134523-03-8

产品性质

• 外观: White Solid
• 熔点: 176-178°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

参考文献

• Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993)
• Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1993)
• Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (1993)