rac-AS-703026-d5

• 产品号: A780102
• 分子式: C15H15FIN3O3
• 分子量: 431.2007732

产品别名

• 标题: rac-AS-703026-d5
• IUPAC标准名: N-[dihydroxy(^2H₅)propyl]-3-[(2-fluoro-4-iodophenyl)amino]pyridine-4-carboxamide
• IUPAC传统名: N-[dihydroxy(^2H₅)propyl]-3-[(2-fluoro-4-iodophenyl)amino]pyridine-4-carboxamide
• 别名: N-[(2R,S)-2,3-Dihydroxypropyl-d5]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide

产品详细信息

详细说明 (English)

Labelled AS703026 (A780100). AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor, in human multiple myeloma (MM). AS703026 induces pleiotropic anti-myeloma activity in vitro and in vivo. MEK inhibitors are useful in the treatment of hyper

参考文献

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• Kolch, W., et al.: Biochem. J., 351, 289 (1995)
• Smith, M., et al.: Leukemia, 17, 274 (1995)
• Adjei, A., et al.: J. Clin. Oncol., 26, 2139 (1995)