ent-Aprepitant

• 产品号: A729790
• CAS号: 172822-29-6
• 分子式: C23H21F7N4O3
• 分子量: 534.4266624

产品别名

• 标题: ent-Aprepitant
• IUPAC标准名: 3-{[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
• IUPAC传统名: 5-{[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-2,4-dihydro-1,2,4-triazol-3-one
• 别名: 5-[[(2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; [2S-[2α(R*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

产品登记号

• CAS号: 172822-29-6

产品详细信息

详细说明 (English)

The (S,R,S)-enantiomer of Aprepitant (A729800), an unwanted enantiomer of Aprepitant in bulk drug and formulation samples of Aprepitant.

参考文献

• Chawla, S., et al.: Cancer, 97, 2290 (2003)
• Huskey, S., et al.: Drug Metab. Dispos., 31, 785 (2003)
• Warr, D., et al.: Eur. J. Cancer, 41, 1278 (2003)