(R,R,R)-Aprepitant

• 产品号: A729785
• CAS号: 1148113-53-4
• 分子式: C23H21F7N4O3
• 分子量: 534.4266624

产品别名

• 标题: (R,R,R)-Aprepitant
• IUPAC标准名: 3-{[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
• IUPAC传统名: 5-{[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-2,4-dihydro-1,2,4-triazol-3-one
• 别名: 5-[[(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

产品登记号

• CAS号: 1148113-53-4

产品详细信息

详细说明 (English)

The (R,R,R)-enantiomer of Aprepitant (A729800), the key intermediate of Aprepitant in bulk drug and formulation samples of Aprepitant.

参考文献

• Chawla, S., et al.: Cancer, 97, 2290 (2003)
• Huskey, S., et al.: Drug Metab. Dispos., 31, 785 (2003)
• Warr, D., et al.: Eur. J. Cancer, 41, 1278 (2003)