Atorvastatin Lactone

• 产品号: A791780
• CAS号: 125995-03-1
• 分子式: C33H33FN2O4
• 分子量: 540.6245232
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Atorvastatin Lactone
• IUPAC标准名: 5-(4-fluorophenyl)-1-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-N,4-diphenyl-2-(propan-2-yl)-1H-pyrrole-3-carboxamide
• IUPAC传统名: 5-(4-fluorophenyl)-1-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-2-isopropyl-N,4-diphenylpyrrole-3-carboxamide
• 别名: 5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin δ-Lactone

产品登记号

• CAS号: 125995-03-1

产品性质

• 外观: Off-White to Pale Yellow Solid
• 熔点: 103-106°C
• 溶解度: DMF
• 溶解度: DMSO
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.

参考文献

• Boyd, R., et al.: J. Clin. Pharmacol., 40, 91, (2000)
• Bogman, K., et al.: Br. J. Pharmacol., 132, 1183 (2000)
• Backman, J., et al.: Clin. Pharmacol. Ther., 72, 685 (2000)
• Kalvass, J., et al.: Drug Metab. Dispos., 35, 455(2000)