Andrographolide

• 产品号: A637475
• CAS号: 5508-58-7
• 分子式: C20H30O5
• 分子量: 350.4492
• 保 存: Refrigerator

产品别名

• 标题: Andrographolide
• IUPAC标准名: (4E,5R)-4-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}-5-hydroxyoxolan-3-one
• IUPAC传统名: (4E,5R)-4-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-hexahydro-1H-naphthalen-1-yl]ethylidene}-5-hydroxyoxolan-3-one
• 别名: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Andrographis; [1R-[1α[E(S*)],4aβ,5α,6α,8aα]]-3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Andrographolid; 3α,14,15,18-Tetrahydroxy-5β,9βH,10α-labda-8(20),12-dien-16-oic Acid γ-Lactone

产品登记号

• CAS号: 5508-58-7

产品性质

• 外观: White Solid
• 熔点: 232-235°C
• 溶解度: DMSO
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M.

参考文献

• Chander, R. et al.: Int. J. Pharmacog., 33, 135 (1995)
• Chen, H.-W. et al.: J. Nat. Prod., 74, 2408 (1995)
• J. Agric. Food Chem., 59, 5263 (1995)