Anacetrapib

• 产品号: A637200
• CAS号: 875446-37-0
• 分子式: C30H25F10NO3
• 分子量: 637.508432

产品别名

• 标题: Anacetrapib
• IUPAC标准名: (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-({2-[4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]-5-(trifluoromethyl)phenyl}methyl)-4-methyl-1,3-oxazolidin-2-one
• IUPAC传统名: anacetrapib
• 别名: (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl]-4-methyl-1,3-oxazolidin-2-one; MK 0859; (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-2-oxazolidinone

产品登记号

• CAS号: 875446-37-0

产品详细信息

详细说明 (English)

An orally active and potent cholesterol ester transfer protein (CETP) inhibitor for the treatment of atherosclerosis, in particular dyslipidemia.

参考文献

• Krishna, R. et al.: Br. J. Clin. Pharmacol., 67, 520 (2009)
• Vergeer, M. et al.: Nat. Clin. Pract. Cardiovasc. Med., 5, 302 (2009)
• Masson, D.: Curr. Opin. Invest. Drugs, 10, 980 (2009)