Amrubicinol (Mixture of Diastereomers)

• 产品号: A635210
• CAS号: 186353-53-7
• 分子式: C25H27NO9
• 分子量: 485.48318

产品别名

• 标题: Amrubicinol (Mixture of Diastereomers)
• IUPAC标准名: (7S,9S)-9-amino-7-{[(2S,4R,5R)-4,5-dihydroxyoxan-2-yl]oxy}-6,11-dihydroxy-9-(1-hydroxyethyl)-5,7,8,9,10,12-hexahydrotetracene-5,12-dione
• IUPAC传统名: (7S,9S)-9-amino-7-{[(2S,4R,5R)-4,5-dihydroxyoxan-2-yl]oxy}-6,11-dihydroxy-9-(1-hydroxyethyl)-8,10-dihydro-7H-tetracene-5,12-dione
• 别名: 13-Hydroxy SM 5887; (7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione

产品登记号

• CAS号: 186353-53-7

产品详细信息

详细说明 (English)

A metabolite of Amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug.

参考文献

• Oken, M., et al.: Am. J. Clin. Oncol., 5, 649 (1982)
• Ohara, H., et al.: Biochem. Pharmacol., 50, 221 (1982)
• de Jongh, F., et al.: J. Clin. Oncol., 19, 3733 (1982)
• Backstrom, G., et al.: Eur. J. Pharm. Sci., 18, 359 (1982)