Amonafide-d6

• 产品号: A634207
• 分子式: C16H17N3O2
• 分子量: 283.32508

产品别名

• 标题: Amonafide-d6
• IUPAC标准名: 11-amino-3-{2-[bis(^2H₃)methylamino]ethyl}-3-azatricyclo[7.3.1.0^5,^1^3]trideca-1(13),5,7,9,11-pentaene-2,4-dione
• IUPAC传统名: 11-amino-3-{2-[bis(^2H₃)methylamino]ethyl}-3-azatricyclo[7.3.1.0^5,^1^3]trideca-1(13),5,7,9,11-pentaene-2,4-dione
• 别名: 5-Amino-2-[2-(dimethylamino-d6)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione; NCI 308847-d6; MADE-FA 142-d6; FA 142-d6; M-FA 142-d6; NSC 308847-d6; Nafidimide-d6

产品详细信息

详细说明 (English)

Labelled Amonafide. It is a DNA intercalator and topoisomerase II inhibitor in clinical development for the treatment of neoplastic diseases. Antitumor agent.

参考文献

• Hsiang, Y., et al.: Mol. Pharmacol., 36, 371 (1989)
• Costanza, M., et al.: Clin. Cancer Res., 1, 699 (1989)
• Innocenti, F., et al.: Drug Metab. Dispos., 29, 596 (1989)
• Brana, M., et al.: J. Med. Chem., 47, 1391 (1989)