(R)-Amlodipine Hemi-dibenzoyl-L-tartrate

• 产品号: A633505
• 分子式: C38H39ClN2O13
• 分子量: 767.17486

产品别名

• 标题: (R)-Amlodipine Hemi-dibenzoyl-L-tartrate
• IUPAC标准名: (2R,3R)-2,3-bis(benzoyloxy)butanedioic acid 3-ethyl 5-methyl (4R)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC传统名: (2R,3R)-2,3-bis(benzoyloxy)butanedioic acid; (R)-amlodipine
• 别名: (R)-(+)-Amlodipine Hemi-dibenzoyl-L-tartrate; (+)-Amlodipine Hemi-dibenzoyl-L-tartrate; (4R)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Hemi-dibenzoyl-L-tartrate; d-Amlodipine Hemi-dibenzoyl-L-tartrate

产品性质

• 外观: Off-White Solid
• 溶解度: Methanol

产品详细信息

详细说明 (English)

(R)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

参考文献

• Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986)
• Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1986)
• Haria, M., et al.: Drugs, 50, 560 (1986)