(R)-Amlodipine-d4

• 产品号: A633492
• 分子式: C20H25ClN2O5
• 分子量: 408.8759
• 保 存: -20°C Freezer

产品别名

• 标题: (R)-Amlodipine-d4
• IUPAC标准名: 3-ethyl 5-methyl (4R)-2-{[2-amino(^2H₄)ethoxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC传统名: 3-ethyl 5-methyl (4R)-2-{[2-amino(^2H₄)ethoxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• 别名: (R)-(+)-Amlodipine-d4; d-Amlodipine-d4; (+)-Amlodipine-d4; (4R)-2-[[2-Amino(ethoxy-d4)]ethyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester

产品性质

• 外观: White Solid
• 熔点: 106-108°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A labelled (R)-enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

参考文献

• Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986)
• Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1986)
• Haria, M., et al.: Drugs, 50, 560 (1986)