9-Amino-1,2,3,4-tetrahydroacridine Hydrochloride Dihydrate

• 产品号: A629700
• CAS号: 1684-40-8
• 分子式: C13H15ClN2
• 分子量: 234.7246
• 保 存: -20°C Freezer

产品别名

• 标题: 9-Amino-1,2,3,4-tetrahydroacridine Hydrochloride Dihydrate
• IUPAC标准名: 1,2,3,4-tetrahydroacridin-9-amine hydrochloride
• IUPAC传统名: tacrine hydrochloride
• 别名: 1,2,3,4-Tetrahydro-9-Acridinamine Hydrochloride Dihydrate; Tacrine Hydrochloride Dihydrate; Tenakrin Dihydrate; THA Dihydrate; Hydroaminacrine Dihydrate; Romotal Dihydrate

产品登记号

• CAS号: 1684-40-8

产品性质

• 外观: Pale Yellow Solid
• 熔点: 284-286°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A potent centrally acting anticholinesterase, for therapy of memory deficits in patients with Alzheimers's disease. THA also selectively blocks potassium channels in the central nervous system, which results in an increased release of acetylcholine and

参考文献

• Harper, J., et al.: Chem. Biol., 4, 119 ( 1997), Kirkitadze, M., et al.: J. Mol. Biol., 312, 1103 (2001)
• Zhuang, Z., et al.: J. Med. Chem., 44, 1905 (2001)
• Necula, M.J., et al.: Biol. Chem., 282, 10311 (2001)