(3S,4aS,8aS)-2-[(2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl]-N-(1,1-dimethylethyl)decahydro-3-isoquinolinecarboxamide-d9

• 产品号: A611582
• 分子式: C24H39N3O2
• 分子量: 401.58536

产品别名

• 标题: (3S,4aS,8aS)-2-[(2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl]-N-(1,1-dimethylethyl)decahydro-3-isoquinolinecarboxamide-d9
• IUPAC标准名: (3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-[2-(^2H₃)methyl(^2H₆)propan-2-yl]-decahydroisoquinoline-3-carboxamide
• IUPAC传统名: (3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-[2-(^2H₃)methyl(^2H₆)propan-2-yl]-octahydro-1H-isoquinoline-3-carboxamide
• 别名: [3S-[2(2S*,3R*),3α,4aβ,8aβ]]-2-(3-Amino-2-hydroxy-4-phenylbutyl)-N-(1,1-dimethylethyl-d9)decahydro-3-isoquinolinecarboxamide

产品详细信息

详细说明 (English)

(3S,4aS,8aS)-2-[(2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl]-N-(1,1-dimethylethyl)decahydro-3-isoquinolinecarboxamide-d9 is a labelled intermediate in the synthesis of Saquinavir (S135000).

参考文献

• Greenwood, B., et al.: Lancet, 365, 1487 (2005)
• Andrews, K., et al.: Antimicrob. Agents Chemother., 50, 639 (2005)
• Ersmark, K., et al.: Bioorg. Med. Chem., 14, 2197 (2005)