N-(2-Aminoethyl) Cyclopamine

• 产品号: A608925
• CAS号: 334616-31-8
• 分子式: C29H46N2O2
• 分子量: 454.68774
• 保 存: -20°C Freezer

产品别名

• 标题: N-(2-Aminoethyl) Cyclopamine
• IUPAC标准名: (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-4'-(2-aminoethyl)-3',6',10,11b-tetramethyl-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3'H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-3-ol
• IUPAC传统名: (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-4'-(2-aminoethyl)-3',6',10,11b-tetramethyl-2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a-hexadecahydro-1H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-3-ol
• 别名: (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-4'-(2-aminoethyl)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol

产品登记号

• CAS号: 334616-31-8

产品性质

• 外观: Off-White Solid
• 熔点: >175°C (dec.)
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A deriviative of Cyclopamine, which demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1

参考文献

• Taipale, J., et al.: Nature, 406, 1005 (2000)
• Perron, M., et al.: Development, 130, 1565 (2003)