4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine

• 产品号: A603004
• CAS号: 221243-82-9
• 分子式: C19H19N5
• 分子量: 317.38766
• 保 存: -20°C Freezer

产品别名

• 标题: 4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine
• IUPAC标准名: 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• IUPAC传统名: 1-tert-butyl-3-(naphthalen-1-yl)pyrazolo[3,4-d]pyrimidin-4-amine
• 别名: 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-NA-PP1

产品登记号

• CAS号: 221243-82-9

产品性质

• 外观: White to Off-White Solid
• 熔点: 219-222°C
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A highly potent (IC50=1.5nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase.

参考文献

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• Regan, J., et al.: J. Med. Chem., 45, 2994 (1999)
• Bain, J., et al.: Biochem. J., 371, 199 (1999)
• Kuma, Y., et al.: J. Biol. Chem., 280, 19472 (200