7-Allyl-7,8-dihydro-8-oxoguanosine(Loxoribine)

• 产品号: A550000
• CAS号: 121288-39-9
• 分子式: C13H17N5O6
• 分子量: 339.30398
• 保 存: Refrigerator, Under Inert Atmosphere

产品别名

• 标题: 7-Allyl-7,8-dihydro-8-oxoguanosine(Loxoribine)
• IUPAC标准名: 2-amino-9-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-(prop-2-en-1-yl)-6,7,8,9-tetrahydro-1H-purine-6,8-dione
• IUPAC传统名: 2-amino-9-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-(prop-2-en-1-yl)-1H-purine-6,8-dione
• 别名: 7-Allyl-2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7,9-dihydro-1H-purine-6,8-dione, Loxoribine

产品登记号

• CAS号: 121288-39-9

产品性质

• 外观: White Solid
• 熔点: 227-230°C
• 溶解度: DMSO
• 保存条件: Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

7-Allyl-7,8-dihydro-8-oxoguanosine (Loxoribine) is a small-molecule immunostimulant. Loxoribine is a toll-like receptor 7 (TLR7) agonist; induces immune cell activation and increases cytokine production. Loxoribine displays antitumor and antiviral activi

参考文献

• Goodman, M.G., et al.: J. Immunol., 135, 3284 (1985)
• Reitz, A. B., et al.: J. Med. Chem., 37, 3561 (1994)