Aliskiren-d6 Hydrochloride

• 产品号: A536002
• 分子式: C30H54ClN3O6
• 分子量: 588.21926
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Aliskiren-d6 Hydrochloride
• IUPAC标准名: (2S,4S,5S,7S)-5-amino-N-[2-carbamoyl-2,2-bis(^2H₃)methylethyl]-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide hydrochloride
• IUPAC传统名: (2S,4S,5S,7S)-5-amino-N-[2-carbamoyl-2,2-bis(^2H₃)methylethyl]-4-hydroxy-2-isopropyl-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methylnonanamide hydrochloride
• 别名: Tekturna Hydrochloride-d6; CGP 60536-d6; CGP60536B-d6; Rasilez-d6 Hydrochloride; (αS,γS,δS,ζS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeneoctanamide-d6 Hydrochloride; SPP 100-d6

产品性质

• 外观: Light Tan Solid
• 熔点: 103-105°C
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An orally active, labelled synthetic nonpeptide renin inhibitor. Antihypertensive.

参考文献

• Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000)
• Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2000)
• Wood, J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2000)
• Grandman, A.H., et al.: Circulation, 111, 1012 (2000)