N-(5-Adamant-1-yl-methoxy)pentyl Deoxynojirimycin

• 产品号: A210000
• CAS号: 216758-20-2
• 分子式: C22H39NO5
• 分子量: 397.54876

产品别名

• 标题: N-(5-Adamant-1-yl-methoxy)pentyl Deoxynojirimycin
• IUPAC标准名: (3R,4R)-1-[5-(adamantan-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
• IUPAC传统名: (3R,4R)-1-[5-(adamantan-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
• 别名: (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-(tricyclo[3.3.1.13,7]dec-1-ylmethoxy)pentyl]-3,4,5-piperidinetriol

产品登记号

• CAS号: 216758-20-2

产品性质

• 外观: Off White Foam
• 溶解度: Ethanol
• 溶解度: Methanol

产品详细信息

详细说明 (English)

A powerful inhibitor of the non-lysomal glucoceramidase at nanomolar concentrations. At these low concentrations, the lysosomal glucocerebrosidase and a-glucosidase, the glucoceramide synthetase, and the N-linked glycantrimming a-glucosidases of the endop

参考文献

• Jeckel, D., et al.: J. Cell Biol., 117, 259 (1992)
• Kato, A., et al.: J. Med. Chem., 48, 2036 (1992)
• Sakabe, K., et al.: J. Biol. Chem., 285, 34460 (1992)