O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate

• 产品号: A157250
• CAS号: 132489-69-1
• 分子式: C15H19N3O7
• 分子量: 353.32726
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate
• IUPAC标准名: [(3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-ylidene]amino N-phenylcarbamate
• IUPAC传统名: [(3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-ylidene]amino N-phenylcarbamate
• 别名: PugNAc; (Z)-PugNAc; 2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-gluconimidic Acid δ-Lactone

产品登记号

• CAS号: 132489-69-1

产品性质

• 外观: White to Off-White Solid
• 熔点: 172-175°C
• 溶解度: DMSO
• 溶解度: Hot Ethanol
• 溶解度: Hot Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An inhibitor of O-GlcNAcase, hexosaminidase A, and hexosaminidase B.

参考文献

• Baji, H., et al,: Eur. J. Med. Chem., 30, 617 (1995)
• Vaaje-Kolstad, G., et al.: J. Biol. Chem., 279, 3612 (1995)
• Perreira, M., et al.: Bioorg. Med. Chem., 14, 837 (2006).