2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconohydroximo-1,5-lactone

• 产品号: A142425
• CAS号: 132063-03-7
• 分子式: C15H18N2O6
• 分子量: 322.31322

产品别名

• 标题: 2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconohydroximo-1,5-lactone
• IUPAC标准名: N-[(4aR,7R,8R,8aS)-8-hydroxy-6-(hydroxyimino)-2-phenyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-7-yl]acetamide
• IUPAC传统名: N-[(4aR,7R,8R,8aS)-8-hydroxy-6-(hydroxyimino)-2-phenyl-hexahydropyrano[3,2-d][1,3]dioxin-7-yl]acetamide
• 别名: 2-(Acetylamino)-2-deoxy-N-hydroxy-4,6-O-[(R)-phenylmethylene]-D-gluconimidic Acid δ-Lactone

产品登记号

• CAS号: 132063-03-7

产品性质

• 外观: Off-White Solid
• 熔点: 229-231°C
• 溶解度: DMSO
• 溶解度: Methanol

产品详细信息

详细说明 (English)

2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconohydroximo-1,5-lactone is used in synthesis of 2-acetamido-2-deoxy-D-gluconohydroximolactone (PUGNAc), a strong inhibitor of β-N-acetylglucosaminidases.

参考文献

• Horsch, M., et al.: Eur. J. Biochem., 197, 815 (1991)
• Horsch, M., et al.: Eur. J. Biochem., 237, 476 91996), Fernandes, M., et al.: J. Biol. Chem., 272, 814 (1991)