Abiraterone Acetate

• 产品号: A108500
• CAS号: 154229-18-2
• 分子式: C26H33NO2
• 分子量: 391.54572
• 保 存: -20°C Freezer

产品别名

• 标题: Abiraterone Acetate
• IUPAC标准名: (1S,2R,5R,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3-yl)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-7,13-dien-5-yl acetate
• IUPAC传统名: (1S,2R,5R,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3-yl)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-7,13-dien-5-yl acetate
• 别名: (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester); CB 7630

产品登记号

• CAS号: 154229-18-2

产品性质

• 外观: Off-White to Pale Yellow Solid
• 熔点: 127-130°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Abiraterone acetate is a novel steroidal inhibitor of human Cytochrome P450 (17α-Hydroxylase-C17,20-lyase): potential agent for the treatment of prostatic cancer.

参考文献

• Denis, L., et al.: Cancer, 72, 3888 (1993)
• Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1993)
• Denmeade, S., et al.: Nat. Rev., 2, 389(1993)
• Scher, H., et al.: J. Clin. Oncol., 23, 8253 (1993)