Phosphoramidon disodium salt

• 产品号: 83645
• CAS号: 119942-99-3
• 分子式: C23H32N3Na2O10P
• 分子量: 587.467581
• 纯 度: ≥97.0% (TLC)

产品别名

• 标题: Phosphoramidon disodium salt
• IUPAC标准名: disodium (2S)-3-(1H-indol-3-yl)-2-[(2S)-4-methyl-2-[({[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}phosphinato)amino]pentanamido]propanoate
• IUPAC传统名: disodium (2S)-3-(1H-indol-3-yl)-2-[(2S)-4-methyl-2-({[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphosphinato}amino)pentanamido]propanoate
• 别名: N-(α-Rhamno-pyranosyl-phos-phono)-L-leucyl-L-tryptophan disodium salt; N-(α-Rhamno-pyranosyl-oxy-hydroxy-phosphinyl)-Leu-Trp disodium salt

产品登记号

• MDL号: MFCD00077870
• CAS号: 119942-99-3
• Beilstein号: 8105669

产品性质

• Empirical Formula (Hill Notation): C23H32N3Na2O10P
• 杂质: ≤6% water
• 纯度: ≥97.0% (TLC)
• 溶解度: acetic acid: soluble20 mg/mL, clear, colorless to light yellow-green
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Identification of phosphoramidon as a metallo-endopeptidase inhibitor was used to characterize endothelin converting enzyme as a metallo-endopeptidase.1 Phosphoramidon increases the production of β-amyloid protein, but not amyloid precursor protein, indicating that abnormal amyloid processing in Alzheimer′s disease may be carried out by a metallo-endopeptidase.2
Other Notes
Naturally occurring thermolysin inhibitor3; Mode of binding4

详细说明 (简体中文)

Application
Identification of phosphoramidon as a metallo-endopeptidase inhibitor was used to characterize endothelin converting enzyme as a metallo-endopeptidase.1 Phosphoramidon increases the production of β-amyloid protein, but not amyloid precursor protein, indicating that abnormal amyloid processing in Alzheimer′s disease may be carried out by a metallo-endopeptidase.2
Other Notes
Naturally occurring thermolysin inhibitor3; Mode of binding4