4-Maleimidobutyric acid N-hydroxysuccinimide ester

• 产品号: 63175
• CAS号: 80307-12-6
• 分子式: C12H12N2O6
• 分子量: 280.23348
• 纯 度: ≥98.0% (HPLC)

产品别名

• 标题: 4-Maleimidobutyric acid N-hydroxysuccinimide ester
• IUPAC标准名: 2,5-dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate
• IUPAC传统名: 2,5-dioxopyrrolidin-1-yl 4-(2,5-dioxopyrrol-1-yl)butanoate
• 别名: 4-Maleimidobutyric acid N-succinimidyl ester; N-(γ-Maleimidobutyryloxy)succinimide; GMBS; N-Succinimidyl 4-maleimidobutyrate

产品登记号

• MDL号: MFCD00036817
• Beilstein号: 6427689
• CAS号: 80307-12-6
• PubChem SID: 24882441

产品性质

• Empirical Formula (Hill Notation): C12H12N2O6
• 纯度: ≥98.0% (HPLC)
• 熔点: 123-129 °C
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.

详细说明 (简体中文)

Application
A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.