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Budesonide

产品号 PHR1178 公司名称 Sigma Aldrich
CAS号 51333-22-3 公司网站 http://www.sigmaaldrich.com
分子式 C25H34O6 电 话 1-800-521-8956
分子量 430.53386 传 真
纯 度 电子邮件
保 存 Chembase数据库ID: 132753

产品价格信息

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产品别名

标题
Budesonide
IUPAC标准名
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
IUPAC传统名
budesonide
别名
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione

产品登记号

MDL号 MFCD00083259
EC号 257-139-7
CAS号 51333-22-3

产品性质

Empirical Formula (Hill Notation) C25H34O6
级别 certified reference material
包装 pkg of 500 mg
Pharmacopeia Traceability traceable to BP 793
Pharmacopeia Traceability traceable to PhEur B1157300
Pharmacopeia Traceability traceable to USP 1078201
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德国WGK号 3

产品详细信息

详细说明 (简体中文)
General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO Guide 34.
Other Notes
Values of analytes vary lot to lot.
Biochem/physiol Actions
Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.
详细说明 (English)
General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO Guide 34.
Other Notes
Values of analytes vary lot to lot.
Biochem/physiol Actions
Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.

参考文献