Scutellarin

• 产品号: 73577
• CAS号: 27740-01-8
• 分子式: C21H18O12
• 分子量: 462.36042
• 纯 度: ≥98.0% (HPLC)

产品别名

• 标题: Scutellarin
• IUPAC标准名: (2S,3S,4S,5R,6S)-6-{[5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC传统名: scutellarin
• 别名: 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid; Scutellarein-7-O-β-D-glucuronide; Breviscapin

产品登记号

• MDL号: MFCD01861503
• Beilstein号: 71779
• CAS号: 27740-01-8

产品性质

• Empirical Formula (Hill Notation): C21H18O12
• 级别: analytical standard
• 纯度: ≥98.0% (HPLC)
• 有效期: (limited shelf life, expiry date on the label)
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

详细说明 (简体中文)

Biochem/physiol Actions
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.