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克雷伯氏菌选择性添加剂_分子结构_CAS_)
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克雷伯氏菌选择性添加剂

产品号 15821 公司名称 Sigma Aldrich
CAS号 公司网站 http://www.sigmaaldrich.com
分子式 C17H18N2O6S 电 话 1-800-521-8956
分子量 378.39962 传 真
纯 度 电子邮件
保 存 Chembase数据库ID: 460

产品价格信息

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产品别名

标题
Klebsiella Selective Supplement
IUPAC标准名
(2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
IUPAC传统名
carbenicillin
别名
Carbenicillin
α-Carboxybenzylpenicillin solution
羧苄青霉素
α-Carboxybenzylpenicillin 溶液

产品登记号

EC号 225-171-0
MDL号 MFCD00242604

产品性质

Empirical Formula (Hill Notation) C17H18N2O6S
级别 for microbiology
有效期 (limited shelf life, expiry date on the label)
GHS危险品标识 GHS08
GHS警示词 Danger
GHS危险声明 H317-H334
欧盟危险性物质标志 有害性(Harmful) 有害性(Harmful) (Xn)
MSDS下载 下载链接
个人保护装置 dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS警示性声明 P261-P280-P342 + P311
危险公开号 42/43
RTECS编号 ON9104700
安全公开号 22-36/37-45
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Components
(per vial, sufficient for 500 ml medium)Carbenicillin 25 mg
Application
For selective isolation and detection of Klebsiella species.
Biochem/physiol Actions
The antibiotic carbenicillin, an ampicillin analog, is a commonly used selection agent that binds and inhibits enzymes involved in the synthesis of the bacterial cell wall. It is active against most isolates of Pseudomonas aerogenosa and certain indole-positive Proteus strains that are resistant to ampicillin. The gene conferring resistance to ampicillin and its analogs, ampr, codes for the enzyme β-lactamase. Carbenicillin is less sensitive to β-lactamase than ampicillin. In addition it has a superior stability at low pH. Experiments have shown that the use of carbenicillin in place of ampicillin helps prevent overgrowth of satellite colonies. Effective concentration: 50 to 100 μg/ml.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 15821.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
详细说明 (简体中文)
Components
(每瓶,足够用于 500mL 培养基) 羧苄青霉素 25mg
Application
用于选择性分离和检测克雷伯氏菌。
Biochem/physiol Actions
羧苄青霉素是氨苄青霉素的类似物,是一种常用的选择剂,它可以结合并抑制细菌细胞壁合成中涉及到的酶。它对耐氨苄青霉素的大多数铜绿假单胞菌分离株以及某些吲哚阳性变形杆菌?均有效。氨苄青霉素及其类似物抗性基因 ampr 编码 β-内酰胺酶。羧苄青霉素比氨苄青霉素对 β-内酰胺酶的敏感性更弱。此外它在低 pH 下具有优异的稳定性。实验表明,用羧苄青霉素替代氨苄青霉素有助于防止卫星菌落的过度生长。有效浓度:50 至 100μg/mL。
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 15821.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

参考文献