N-(2-Aminoethyl)-5-isoquinolinesulfonamide hydrochloride

• 产品号: 06725
• CAS号: 116970-50-4
• 分子式: C11H14ClN3O2S
• 分子量: 287.76576
• 纯 度: ≥97.0% (HPLC)

产品别名

• 标题: N-(2-Aminoethyl)-5-isoquinolinesulfonamide hydrochloride
• IUPAC标准名: N-(2-aminoethyl)isoquinoline-5-sulfonamide hydrochloride
• IUPAC传统名: N-(2-aminoethyl)isoquinoline-5-sulfonamide hydrochloride
• 别名: H-9

产品登记号

• Beilstein号: 6548866
• CAS号: 116970-50-4
• MDL号: MFCD00083242

产品性质

• Empirical Formula (Hill Notation): C11H13N3O2S · HCl
• 纯度: ≥97.0% (HPLC)
• 溶解度: methanol: soluble1 mg/mL, clear, colorless
• GHS警示词: Warning
• GHS危险声明: H302-H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• RTECS编号: NX4897000
• 安全公开号: 26-36
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Selective casein kinase 1 inhibitor1. Potent inhibitor of histamine release from human basophils when induced by phorbol ester or DiC8, but not when induced by anti-IgE, fMLP (formyl-Met-Leu-Phe) and calcium ionophore A23187.2 This implicates divergent pathways of basophil activation.

详细说明 (简体中文)

Biochem/physiol Actions
Selective casein kinase 1 inhibitor1. Potent inhibitor of histamine release from human basophils when induced by phorbol ester or DiC8, but not when induced by anti-IgE, fMLP (formyl-Met-Leu-Phe) and calcium ionophore A23187.2 This implicates divergent pathways of basophil activation.