异腈甲基膦酸二乙酯

• 产品号: 58833
• CAS号: 41003-94-5
• 分子式: C6H12NO3P
• 分子量: 177.138141
• 纯 度: ≥97.0% (GC)

产品别名

• 标题: Diethyl isocyanomethylphosphonate
• IUPAC标准名: diethyl (isocyanomethyl)phosphonate
• IUPAC传统名: diethyl isocyanomethylphosphonate
• 别名: Isocyanomethylphosphonic acid diethyl ester

产品登记号

• CAS号: 41003-94-5
• PubChem SID: 24881211
• Beilstein号: 4674920
• MDL号: MFCD00042951

产品性质

• 级别: purum
• 线性分子式: CNCH2P(O)(OC2H5)2
• 纯度: ≥97.0% (GC)
• 沸点: 84-87 °C/0.1 mmHg(lit.)
• 密度: 1.105 g/mL at 25 °C(lit.)
• 闪点: 113 °C
• 闪点: 235.4 °F
• 折射率: n20/D 1.433(lit.)
• GHS警示词: Warning
• GHS危险声明: H302 + H312 + H332-H315-H319-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS警示性声明: P261-P280-P305 + P351 + P338
• 危险公开号: 20/21/22-36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Other Notes
Prep. of phosphonic acid analogs of amino acids6,7,8; Synthesis of aldehydes from carbonyl compounds9,10
Application
Reactant for:
• Copper-catalyzed cycloaddition reactions1
• Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase2
• Synthesis of sterol analogs as antifungal agents against plant pathogens3
• Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions4
• The Passerini reaction5

详细说明 (简体中文)

Other Notes
制备 α-氨基酸的膦酸类似物6,7,8；由羰基化合物合成醛9,10
Application
Reactant for:
• Copper-catalyzed cycloaddition reactions1
• Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase2
• Synthesis of sterol analogs as antifungal agents against plant pathogens3
• Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions4
• The Passerini reaction5