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Iberiotoxin
产品号	56718	公司名称	Sigma Aldrich
CAS号	129203-60-7	公司网站	http://www.sigmaaldrich.com
分子式	C179H274N50O55S7	电话	1-800-521-8956
分子量	4230.84786	传真
纯度	≥85% (HPLC)	电子邮件
保存		Chembase数据库ID: 132146

产品价格信息

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产品别名

标题

Iberiotoxin

IUPAC标准名

2-(2-{[10-(6-amino-2-{6-amino-2-[2-(2-{[7,34-bis(4-aminobutyl)-37-{2-[2-(2-{[10-(4-aminobutyl)-22-(3-carboxy-2-{2-[3-carboxy-2-(3-hydroxy-2-{2-[(5-oxopyrrolidin-2-yl)formamido]-3-phenylpropanamido}butanamido)propanamido]-3-methylbutanamido}propanamido)-7-(2-carboxyethyl)-13,19-bis(hydroxymethyl)-6,9,12,15,18,21-hexaoxo-16-(propan-2-yl)-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]formamido}-3-(1H-indol-3-yl)propanamido)-3-hydroxypropanamido]-3-methylbutanamido}-25-benzyl-13-(3-carbamimidamidopropyl)-16,31-bis(carboxymethyl)-28-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-19-(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-4-yl]formamido}-4-(methylsulfanyl)butanamido)acetamido]hexanamido}hexanamido)-7-(3-carbamimidamidopropyl)-6,9-dioxo-1,2-dithia-5,8-diazacycloundecan-4-yl]formamido}-3-(4-hydroxyphenyl)propanamido)-4-carbamoylbutanoic acid

IUPAC传统名

2-(2-{[10-(6-amino-2-{6-amino-2-[2-(2-{[7,34-bis(4-aminobutyl)-37-{2-[2-(2-{[10-(4-aminobutyl)-22-(3-carboxy-2-{2-[3-carboxy-2-(3-hydroxy-2-{2-[(5-oxopyrrolidin-2-yl)formamido]-3-phenylpropanamido}butanamido)propanamido]-3-methylbutanamido}propanamido)-7-(2-carboxyethyl)-13,19-bis(hydroxymethyl)-16-isopropyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]formamido}-3-(1H-indol-3-yl)propanamido)-3-hydroxypropanamido]-3-methylbutanamido}-25-benzyl-13-(3-carbamimidamidopropyl)-16,31-bis(carboxymethyl)-19-isopropyl-28-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-4-yl]formamido}-4-(methylsulfanyl)butanamido)acetamido]hexanamido}hexanamido)-7-(3-carbamimidamidopropyl)-6,9-dioxo-1,2-dithia-5,8-diazacycloundecan-4-yl]formamido}-3-(4-hydroxyphenyl)propanamido)-4-carbamoylbutanoic acid

产品登记号

CAS号	129203-60-7
MDL号	MFCD00131365

产品性质

生物来源	from Buthus tamulus
Empirical Formula (Hill Notation)	C179H274N50O55S7
纯度	≥85% (HPLC)
溶解度	H2O: soluble1 mg/mL, clear, colorless
GHS危险品标识
GHS警示词	Danger
GHS危险声明	H300-H310-H330
欧盟危险性物质标志	剧毒(Highly toxic) (T+)
MSDS下载	下载链接
个人保护装置	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS警示性声明	P260-P264-P280-P284-P301 + P310-P302 + P350
RID/ADR	UN 3462 6.1/PG 2
危险公开号	26/27/28
安全公开号	28-36/37-45
保存温度	-20°C
联合国危险货物等级	6.1
联合国危险货物编号	3462
联合国危险货物包装类别(PG)	2
德国WGK号	3

产品详细信息

详细说明 (English)

Amino Acid Sequence
pGlu-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln [Disulfide Bridges: 7-28; 13-33; 17-35]
Biochem/physiol Actions
Selective and reversible inhibitor of high-conductance calcium-activated potassium channel.

详细说明 (简体中文)