L-Buthionine-sulfoximine

• 产品号: 19175
• CAS号: 83730-53-4
• 分子式: C8H18N2O3S
• 分子量: 222.30512
• 纯 度: ≥96.0% (TLC)

产品别名

• 标题: L-Buthionine-sulfoximine
• IUPAC标准名: (2S)-2-amino-4-[butyl(imino)oxo-λ^6-sulfanyl]butanoic acid
• IUPAC传统名: (2S)-2-amino-4-[butyl(imino)oxo-λ^6-sulfanyl]butanoic acid
• 别名: L-BSO

产品登记号

• Beilstein号: 2367136
• CAS号: 83730-53-4
• MDL号: MFCD00067000

产品性质

• Empirical Formula (Hill Notation): C8H18N2O3S
• 纯度: ≥96.0% (TLC)
• 熔点: 224-228 °C (dec.)
• 比旋光度: [α]20/D +33±1°, c = 1% in 1 M HCl
• 溶解度: H2O: soluble50 mg/mL, clear, colorless to faintly yellow
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: EK7713440
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis.2 Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1
Other Notes
Potent specific inhibitor of γ-glutamylcysteine synthetase2
Application
Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1

详细说明 (简体中文)

Biochem/physiol Actions
Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis.2 Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1
Other Notes
Potent specific inhibitor of γ-glutamylcysteine synthetase2
Application
Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.1