Docetaxel

• 产品号: 01885
• CAS号: 114977-28-5
• 分子式: C43H53NO14
• 分子量: 807.87922
• 纯 度: ≥97.0% (HPLC)

产品别名

• 标题: Docetaxel
• IUPAC标准名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC传统名: docetaxel
• 别名: Taxotere®

产品登记号

• CAS号: 114977-28-5
• PubChem SID: 24845209
• MDL号: MFCD00800737

产品性质

• Empirical Formula (Hill Notation): C43H53NO14
• 级别: purum
• 杂质: ~6% water
• 纯度: ≥97.0% (HPLC)
• 熔点: 186-192 °C (dec.)
• 溶解度: Do you have solubility information on this product that you would like to share?
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: DA4172750
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Do you have application information on this product that you would like to share?
Docetaxel can be used to study antibiotics, cell biology, cell signaling, neuroscience and apoptosis and the cell cycle. Docetaxel has been used to study the prevention of chemotherapy-induced alopecia, as well as the treatment of non-small-cell lung cancer in patients contraindicated for standard chemotherapy. Docetaxel has also been used to study the role of hypoxia-inducible factor-1α and -2α in androgen insensitive prostate cancer cells.
Biochem/physiol Actions
Docetaxel is a taxane anti-cancer agent related to paclitaxel. It binds to and stabilizes the β-tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest and apoptosis.

详细说明 (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Do you have application information on this product that you would like to share?
Docetaxel can be used to study antibiotics, cell biology, cell signaling, neuroscience and apoptosis and the cell cycle. Docetaxel has been used to study the prevention of chemotherapy-induced alopecia, as well as the treatment of non-small-cell lung cancer in patients contraindicated for standard chemotherapy. Docetaxel has also been used to study the role of hypoxia-inducible factor-1α and -2α in androgen insensitive prostate cancer cells.
Biochem/physiol Actions
Docetaxel is a taxane anti-cancer agent related to paclitaxel. It binds to and stabilizes the β-tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest and apoptosis.
法律信息
Taxotere 注册商标 Sanofi-Aventis