桔霉素

• 产品号: 00302
• CAS号: 518-75-2
• 分子式: C13H14O5
• 分子量: 250.24726
• 纯 度: ≥98.0% (TLC)

产品别名

• 标题: Citrinin
• IUPAC标准名: (3R,4S)-8-hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-2-benzopyran-7-carboxylic acid
• IUPAC传统名: antimycin
• 别名: 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid; 桔青霉素

产品登记号

• Beilstein号: 5282243
• MDL号: MFCD00006912
• CAS号: 518-75-2
• EC号: 208-257-2

产品性质

• 生物来源: from Penicillium citrinum
• Empirical Formula (Hill Notation): C13H14O5
• 纯度: ≥98.0% (TLC)
• GHS警示词: Danger
• GHS危险声明: H301-H311-H331-H351
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• GHS警示性声明: P261-P280-P301 + P310-P311
• RID/ADR: UN 3462 6.1/PG 3
• 危险公开号: 23/24/25-40
• RTECS编号: DJ2275000
• 安全公开号: 26-36/37/39-45
• 保存温度: 2-8°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 3462
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

产品详细信息

详细说明 (English)

Biochem/physiol Actions
A mycotoxin found in grains and animal feed that nephrotoxic and is a teratogen in rodents, reducing blastocyst cell number, embryonic survival, and neonatial weight and increasing fetal abnormalities. It′s cytotoxicity to cells in culture are associated with the production of reactive oxygen species, the activation of mitochondrial apoptotic pathways, and the inhibition of antiapoptotic phosphorylation pathways.

详细说明 (简体中文)

Biochem/physiol Actions
A mycotoxin found in grains and animal feed that nephrotoxic and is a teratogen in rodents, reducing blastocyst cell number, embryonic survival, and neonatial weight and increasing fetal abnormalities. It′s cytotoxicity to cells in culture are associated with the production of reactive oxygen species, the activation of mitochondrial apoptotic pathways, and the inhibition of antiapoptotic phosphorylation pathways.