4-Amidinophenylmethanesulfonyl fluoride hydrochloride

• 产品号: 06566
• CAS号: 74938-88-8
• 分子式: C8H10ClFN2O2S
• 分子量: 252.6936032
• 纯 度: ≥97.0% (AT)

产品别名

• 标题: 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
• IUPAC标准名: (4-carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride
• IUPAC传统名: (4-carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride
• 别名: 4-Amidinobenzylsulfonyl fluoride hydrochloride; p-APMSF

产品登记号

• MDL号: MFCD00078902
• CAS号: 74938-88-8
• Beilstein号: 9083148

产品性质

• Empirical Formula (Hill Notation): C8H9FN2O2S · HCl
• 纯度: ≥97.0% (AT)
• 熔点: ~205 °C (dec.)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Other Notes
An irreversible inhibitor of serine proteases4
Application
APMSF was used to study the glucagon-receptor interaction; inhibition of cAMP formation led to the conclusion that there was a previously unexpected serine residue in the active site which may operate on the receptor by a mechanism similar to serine proteases.1
Biochem/physiol Actions
Irreversible inhibitor of serine proteases with lysine or arginine substrate specificities. Effective concentration 10-100 μM. Frequently used to characterize newly discovered proteases.2,3

详细说明 (简体中文)

Other Notes
An irreversible inhibitor of serine proteases4
Application
APMSF was used to study the glucagon-receptor interaction; inhibition of cAMP formation led to the conclusion that there was a previously unexpected serine residue in the active site which may operate on the receptor by a mechanism similar to serine proteases.1
Biochem/physiol Actions
Irreversible inhibitor of serine proteases with lysine or arginine substrate specificities. Effective concentration 10-100 μM. Frequently used to characterize newly discovered proteases.2,3