Nigericin sodium salt

• 产品号: 72445
• CAS号: 28643-80-3
• 分子式: C40H67NaO11
• 分子量: 746.94315
• 纯 度: ≥98.0% (TLC)

产品别名

• 标题: Nigericin sodium salt
• IUPAC标准名: sodium (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoate
• IUPAC传统名: sodium (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoate
• 别名: Helexin C; Antibiotic X464; Azalomycin M; Antibiotic K178; Polyetherin A

产品登记号

• CAS号: 28643-80-3
• Beilstein号: 3892398
• MDL号: MFCD00036825

产品性质

• 生物来源: from Streptomyces hygroscopicus
• Empirical Formula (Hill Notation): C40H67NaO11
• 纯度: ≥98.0% (TLC)
• 溶解度: chloroform: soluble10 mg/mL, clear, colorless
• GHS警示词: Danger
• GHS危险声明: H301-H315-H319-H335
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P261-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 3462 6.1/PG 3
• 危险公开号: 25-36/37/38
• RTECS编号: QT6840000
• 安全公开号: 26-36/37/39-45
• 保存温度: 2-8°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 3462
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K+> Rb+≥ Cs+>> Na+.
Other Notes
As ion-selective electrode - an efficient K+-carrier.1,2
As ion-selective electrode - an efficient K+-carrier1,2

详细说明 (简体中文)

Biochem/physiol Actions
Polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K+> Rb+≥ Cs+>> Na+.
Other Notes
As ion-selective electrode - an efficient K+-carrier.1,2
As ion-selective electrode - an efficient K+-carrier1,2