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L-高精氨酸 盐酸盐_分子结构_CAS_1483-01-8)
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L-高精氨酸 盐酸盐

产品号 53460 公司名称 Sigma Aldrich
CAS号 1483-01-8 公司网站 http://www.sigmaaldrich.com
分子式 C7H17ClN4O2 电 话 1-800-521-8956
分子量 224.68848 传 真
纯 度 ≥98.0% (TLC) 电子邮件
保 存 Chembase数据库ID: 102515

产品价格信息

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产品别名

标题
L-Homoarginine hydrochloride
IUPAC标准名
(2S)-2-amino-6-carbamimidamidohexanoic acid hydrochloride
IUPAC传统名
L-homoarginine hydrochloride
别名
(S)-2-Amino-6-guanidinohexanoic acid hydrochloride

产品登记号

PubChem SID 24878050
MDL号 MFCD00012622
Beilstein号 4016621
EC号 216-045-6
CAS号 1483-01-8

产品性质

线性分子式 H2NC(=NH)NH(CH2)4CH(NH2)CO2H · HCl
纯度 ≥98.0% (TLC)
熔点 213-215 °C(lit.)
溶解度 H2O: soluble50 mg/mL, clear to slightly hazy, faintly yellow
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个人保护装置 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
德国WGK号 3

产品详细信息

详细说明 (简体中文)
Application
The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
Biochem/physiol Actions
Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.
详细说明 (English)
Application
The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
Biochem/physiol Actions
Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.

参考文献