Puromycin dihydrochloride 二盐酸盐 来源于白色链球菌

• 产品号: 82595
• CAS号: 58-58-2
• 分子式: C22H31Cl2N7O5
• 分子量: 544.43144
• 纯 度: ≥98.0% (HPLC)

产品别名

• 标题: Puromycin dihydrochloride from Streptomyces alboniger
• IUPAC标准名: (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride
• IUPAC传统名: puromycin dihydrochloride
• 别名: 3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine 二盐酸盐; 3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine dihydrochloride

产品登记号

• EC号: 200-387-8
• MDL号: MFCD00012691
• Beilstein号: 3853613
• CAS号: 58-58-2

产品性质

• Empirical Formula (Hill Notation): C22H29N7O5 · 2HCl
• 纯度: ≥98.0% (HPLC)
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• RTECS编号: AU7355000
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Other Notes
Causes premature chain termination in protein synthesis by acting as an analog of aminoacyl-tRNA.; Inhibitor of aminopeptidase and enkephalinase. Photoincorporation of puromycin into rat liver ribosomes1; Immunosuppressive effect2
Biochem/physiol Actions
Nucleoside antibiotic. Protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3′-terminal end of aminoacyl-tRNA. Prevents growth of bacteria, protozoa, algae, and mammalian cells. Acts very quickly and can kill 99% of cells within 2 days, the resistance gene (puromycin acetyltransferase) gives very effective protection.

详细说明 (简体中文)

Other Notes
Causes premature chain termination in protein synthesis by acting as an analog of aminoacyl-tRNA.; Inhibitor of aminopeptidase and enkephalinase. Photoincorporation of puromycin into rat liver ribosomes1; Immunosuppressive effect2
Biochem/physiol Actions
Nucleoside antibiotic. Protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3′-terminal end of aminoacyl-tRNA. Prevents growth of bacteria, protozoa, algae, and mammalian cells. Acts very quickly and can kill 99% of cells within 2 days, the resistance gene (puromycin acetyltransferase) gives very effective protection.