(苯并三氮唑-1-基氧基)二哌啶碳鎓六氟磷酸盐

• 产品号: 12792
• CAS号: 190849-64-0
• 分子式: C17H24F6N5OP
• 分子量: 459.3695402
• 纯 度: ≥98.0% (TLC)

产品别名

• 标题: (Benzotriazol-1-yloxy)dipiperidinocarbenium hexafluorophosphate
• IUPAC标准名: (1H-1,2,3-benzotriazol-1-yloxy)bis(piperidin-1-yl)methylium; hexafluoro-λ^5-phosphanuide
• IUPAC传统名: (1,2,3-benzotriazol-1-yloxy)bis(piperidin-1-yl)methylium hexafluorophosphate
• 别名: HBPipU; O-(Benzotriazol-1-yl)-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate; O-苯并三唑-1-基-N,N,N',N'-二(五亚甲基)六氟磷酸脲

产品登记号

• PubChem SID: 24847806
• CAS号: 190849-64-0
• MDL号: MFCD00191769

产品性质

• Empirical Formula (Hill Notation): C17H24F6N5OP
• 纯度: ≥98.0% (TLC)
• 熔点: 206 °C (dec.)
• 溶解度: acetonitrile: soluble0.1 g/mL, clear
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (简体中文)

Other Notes
最近的研究显示该偶联试剂的晶体和溶液结构为胍的 N-氧化物形式，而不是脲化合物3；肽偶联反应的不吸湿强烈反应剂。这是最近报道的双(四亚甲基)衍生物的类似物4
包装
5 g in glass bottle
Application
Reactant used for: comparison of racemization during peptide coupling1 esterification of nucleosides to solid phase supports for oligonucleotide synthesis2

详细说明 (English)

Other Notes
Recent studies show that crystal and solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound3; Non-hygroscopic, extremely reactive reagent for peptide coupling. It is an analogue of the bis(tetramethylene) derivative described recently4
Packaging
5 g in glass bottle
Application
Reactant used for: comparison of racemization during peptide coupling1 esterification of nucleosides to solid phase supports for oligonucleotide synthesis2